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Study identifier: NCT06347159 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Active Not Recruiting

A Study of EDG-7500 in Adults With Hypertrophic Cardiomyopathy (CIRRUS-HCM)

Condition: Hypertrophic Cardiomyopathy  ·  Sponsor: Edgewise Therapeutics, Inc.

PhasePhase 2
Planned participants79
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is being conducted in order to understand the safety and effects of different doses of EDG-7500 as a single dose in adults with obstructive hypertrophic cardiomyopathy (oHCM) and as multiple doses in adults with obstructive or nonobstructive hypertrophic cardiomyopathy (nHCM).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (21)

University of California, San FranciscoSan Francisco, California, United States
Stanford University Hospital / Stanford Health CareStanford, California, United States
Emory ClinicAtlanta, Georgia, United States
Massachusetts General HospitalBoston, Massachusetts, United States
Brigham and Womens HospitalBoston, Massachusetts, United States
Lahey Hospital and Medical CenterBurlington, Massachusetts, United States
Michigan Medicine - Michigan Clinical Research UnitAnn Arbor, Michigan, United States
Saint Luke's Hospital of Kansas CityKansas City, Missouri, United States
Morristown Medical Center (Atlantic Health System)Morristown, New Jersey, United States
North Shore University HospitalManhasset, New York, United States
NYU Langone Health Medical Center - HCM Program Office (Study open to existing NYU patients only)New York, New York, United States
Sanger Heart and Vascular InstituteCharlotte, North Carolina, United States

+ 9 more locations — full list on the registry record.

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