EICHORCondition: Prehabilitation · Sponsor: Military Medical Academy, Belgrade, Serbia
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Postoperative cognitive deficit and its connection with surgery and general anesthesia were first mentioned in the literature in 1955 by Bradford. Cognitive disorders in the postoperative period are postoperative delirium (POD) and postoperative cognitive dysfunction (POCD). POD is an acute dysfunction in cognition, which did not exist preoperatively. Attention deficit disorder is the main symptom of POD and refers to the inability to direct, focus, maintain, or shift attention. Memory impairment, disorientation, or perceptual disturbances may also be present. Cognitive capacity changes in POD patients develop and fluctuate in the first few days after surgery. Unlike POD, there is no formal definition for POCD. Based on data from the existing literature, it is defined as newly diagnosed cognitive deterioration that occurs after surgery. The diagnosis of POCD should be based on pre- and postoperative screening with appropriate psychometric tests. Risk factors for the development of POCD include those related to the surgical procedure, anesthesia, or the patient himself. Compared to less invasive and shorter operations, there is a higher risk of developing POCD after major, invasive, and long-term operations. Additional risk factors are intraoperative (intraoperative bleeding, perioperative transfusion treatment, hypotension) and postoperative complications (respiratory insufficiency, pneumonia, atelectasis, bronchospasm, bronchopleural fistula, and pulmonary edema). Presurgica…
This description comes directly from the study's public registry record.
Vojislava Neskovic, PhD · +381641775320 · vojkan43@gmail.com
Marija Markovic, MD · +38162666653 · markovicmarija@hotmail.com
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Inclusion Criteria: * Older than 60 years * Elective lung resection operations * Patients who can use a phone or tablet * Patients who agreed to participate in the study * Clinical scale of weakness less than 6 * The American Society of Anesthesiologists (ASA) status I, II, III, IV Exclusion Criteria: * Under 60 years of age * Significant psychiatric comorbidity (schizophrenia, depression, alcoholism) * Significant neurological comorbidity (dementia, cerebrovascular insult in the last 6 months, parkinsonism) * Patient's refusal to participate in the study * The inability of the patient to use a tablet or phone * The American Society of Anesthesiologists (ASA) status V and VI * Clinical weakness scale 6 and above
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Military Medical Academy | Belgrade, Serbia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06339268