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Study identifier: NCT06337318 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Comparing Rituximab and Mosunetuzumab Drug Treatments for People With Low Tumor Burden Follicular Lymphoma

Condition: Classic Follicular Lymphoma · Follicular Lymphoma With Unusual Cytological Features  ·  Sponsor: National Cancer Institute (NCI)

PhasePhase 3
Planned participants600
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This phase III trial compares the effectiveness of rituximab to mosunetuzumab in treating patients with follicular lymphoma with a low tumor burden. Rituximab is a monoclonal antibody. It binds to a protein called CD20, which is found on B cells (a type of white blood cell) and some types of cancer cells. This may help the immune system kill cancer cells. Mosunetuzumab is a monoclonal antibody that may interfere with the ability of cancer cells to grow and spread. It is not yet known if giving rituximab or mosunetuzumab works better in treating patients with follicular lymphoma with a low tumor burden.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

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Locations (270)

University of Alabama at Birmingham Cancer CenterBirmingham, Alabama, United StatesRecruiting
Mayo Clinic Hospital in ArizonaPhoenix, Arizona, United StatesRecruiting
Banner University Medical Center - TucsonTucson, Arizona, United StatesRecruiting
University of Arizona Cancer Center-North CampusTucson, Arizona, United StatesRecruiting
Highlands Oncology Group - FayettevilleFayetteville, Arkansas, United StatesRecruiting
University of Arkansas for Medical SciencesLittle Rock, Arkansas, United StatesRecruiting
Highlands Oncology Group - RogersRogers, Arkansas, United StatesRecruiting
Highlands Oncology GroupSpringdale, Arkansas, United StatesRecruiting
Tower Cancer Research FoundationBeverly Hills, California, United StatesRecruiting
City of Hope Comprehensive Cancer CenterDuarte, California, United StatesRecruiting
UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory CareIrvine, California, United StatesRecruiting
City of Hope at Irvine LennarIrvine, California, United StatesRecruiting

+ 258 more locations — full list on the registry record.

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