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Study identifier: NCT06325202 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Closed Loop and Education for Hypoglycemia Awareness Restoration

Condition: Diabetes Mellitus, Type 1  ·  Sponsor: Milton S. Hershey Medical Center

PhaseNA
Planned participants324
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The purpose of the CLEAR study is to determine the effect on counterregulatory responses (CRR) of intervening (by attempting to strictly avoid hypoglycemia) to improve awareness of hypoglycemic symptoms among adults with type 1 diabetes (T1D) who have impaired awareness of hypoglycemia (IAH). IAH affects 20-25% of adults with T1D, and rises with increasing duration of T1D.

This description comes directly from the study's public registry record.

Talk to the study team

Abid Kazi, PhD  ·  717-531-0003  ·  akazi@pennstatehealth.psu.edu

Venus Grella, MPH  ·  717-531-0003  ·  vgrella@pennstatehealth.psu.edu

Always discuss trial participation with your own doctor first.

Locations (8)

University of California, San DiegoLa Jolla, California, United StatesRecruiting
AdventHealthOrlando, Florida, United StatesRecruiting
University of KentuckyLexington, Kentucky, United StatesRecruiting
University of MinnesotaMinneapolis, Minnesota, United StatesRecruiting
University of PennsylvaniaPhiladelphia, Pennsylvania, United StatesRecruiting
University of MelbourneFitzroy, Victoria, AustraliaRecruiting
University of LeicesterLeicester, United KingdomRecruiting
University of SheffieldSheffield, United KingdomRecruiting

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