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Study identifier: NCT06265727 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

A Phase 1/2 Study to Investigate CRB-701 in Solid Tumors

Condition: Solid Tumor, Adult  ·  Sponsor: Corbus Pharmaceuticals Inc.

PhasePhase 1/Phase 2
Planned participants348
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The goal of this clinical trial is to define a safe and effective dose of CRB-701 for participants with solid tumors that are expressing a protein called nectin-4. The main questions it aims to answer are: What is the the safe and effective dose of CRB-701? What cancers can be treated effectively with CRB-701? Participants will be asked to attend clinic and be given a intravenous infusion of CRB-701. They will have blood tests, CT or MRI Scans, and other assessments to measure whether CRB-701 has an effect on tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Ian Hodgson, PhD  ·  +1 (617) 963-0105  ·  Clinical@Corbuspharma.com

Rodney Carter, BSc  ·  Clinical@Corbuspharma.com

Always discuss trial participation with your own doctor first.

Locations (41)

O'Neal Comprehensive Cancer Center at University of Alabama-BirminghamBirmingham, Alabama, United StatesRecruiting
City of Hope Cancer CenterDuarte, California, United StatesRecruiting
Moores Cancer Centre at UC San Diego HealthSan Diego, California, United StatesRecruiting
Helen Diller Family Comprehensive Cancer Center - UCSFSan Francisco, California, United StatesRecruiting
Rocky Mountain Cancer CentresDenver, Colorado, United StatesActive Not Recruiting
Yale Cancer CenterNew Haven, Connecticut, United StatesRecruiting
Florida Cancer SpecialistsOrlando, Florida, United StatesRecruiting
University of ChicagoChicago, Illinois, United StatesRecruiting
Hope and Healing Cancer CenterHinsdale, Illinois, United StatesActive Not Recruiting
Dana-Faber Cancer InstituteBoston, Massachusetts, United StatesRecruiting
Nebraska Hematology OncologyLincoln, Nebraska, United StatesActive Not Recruiting
Carolina BioOncology InstituteHuntersville, North Carolina, United StatesActive Not Recruiting

+ 29 more locations — full list on the registry record.

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