EICHORCondition: Lung Cancer · Sponsor: Assistance Publique - Hôpitaux de Paris
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The objective is to study the phenotypic, functional and metabolomic characteristics of neutrophils circulating subpopulations in lung cancer patients, and to compare them to a control group of healthy volunteers. A blood sample will be taken before the first treatment session for the lung cancer patient and a second blood sample will be taken during the first evaluation visit. The investigators hypothesize that there may be different circulating neutrophil subpopulations in patients with metastatic non-small cell lung cancer (NSCLC) involved in tumor progression and resistance to immunotherapy.
This description comes directly from the study's public registry record.
Marie WISLEZ, Pr · +33 1 58 41 18 89 · marie.wislez@aphp.fr
Marie BENHAMMANI-GODARD · +33 1 58411190 · marie.godard@aphp.fr
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Inclusion Criteria common to lung cancer and COPD patients : * Age ≥ 18 years, * male or female, * affiliated with a Health Insurance, Inclusion Criteria for lung cancer patients : \- Diagnosis of metastatic stage lung cancer with mutation status, naïve treatment Inclusion Criteria for COPD patients : \- Diagnosis of COPD post-smoking Exclusion Criteria: * Tuberculosis or other acute or chronic bacterial infections * Chronic progressive viral infections (Hepatitis B and C, HIV) * Previous or ongoing chemotherapy * Impossibility of giving the subject informed information. * Opposition to the research. * Participation in another research study with an exclusion period still in progress at pre-inclusion (possible inclusion in an observational study) * Vulnerable individual (pregnant, parturient or breastfeeding woman), persons under guardianship or curatorship, or deprived of liberty by a judicial or administrative decision) * Patients benefiting from the AME
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Assistance Publique - Hôpitaux de Paris (AP-HP) - Cochin Hospital - Pneumology unit | Paris, Île-de-France Region, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06244355