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Study identifier: NCT06220864 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Recruiting

SNV1521 in Participants With Advanced Solid Tumors

Condition: Advanced Solid Tumor  ·  Sponsor: Synnovation Therapeutics, Inc.

PhasePhase 1
Planned participants400
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where25 locations · 7 countries

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study is testing a new medicine, SNV1521, for people with advanced cancers. The researchers want to find out if SNV1521 is safe, well-tolerated, and effective in treating solid tumors. They are investigating different doses in order to find the most effective and safe one. They are also investigating whether it can be combined with other cancer therapies.

This description comes directly from the study's public registry record.

Talk to the study team

Robert Casper  ·  443-764-9527  ·  rcasper@synnovationtx.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Advanced or metastatic solid tumor malignancy * Evaluable or Measurable disease (RECIST 1.1 Criteria). * ECOG Performance Status 0 or 1. * Life expectancy \> 3 months Exclusion Criteria: * History of other malignancy within the past 2 years * Prior diagnosis of Myelodysplastic syndrome or Acute Myeloid Leukemia * Significant cardiovascular disease within 6 months * Significant gastrointestinal disease * HIV infection with a CD4+ T-cell count \< 200 cells/μL and/or a detectable viral load * Liver dysfunction

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (25)

Smilow Cancer Hospital at Yale New HavenNew Haven, Connecticut, United StatesRecruiting
Thomas Jefferson UniversityPhiladelphia, Pennsylvania, United StatesRecruiting
Sarah Cannon Research InstituteNashville, Tennessee, United StatesRecruiting
The University of Texas M.D. Anderson Cancer CenterHouston, Texas, United StatesRecruiting
START Center for Cancer CareWest Valley City, Utah, United StatesRecruiting
Scientia Clinical ResearchRandwick, New South Wales, AustraliaRecruiting
Princess Alexandra HospitalWoolloongabba, Queensland, AustraliaRecruiting
Monash HealthClayton, Victoria, AustraliaRecruiting
The Alfred HospitalMelbourne, Victoria, AustraliaRecruiting
Linear Clinical ResearchCrawley, Western Australia, AustraliaRecruiting
The Institut Jules BordetBrussels, BelgiumRecruiting
University Center for Clinical Research Antwerp (UNICCRA)Edegem, BelgiumRecruiting

+ 13 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

New HavenPhiladelphiaNashvilleHouston

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