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Study identifier: NCT06214611 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingART in HNT

Prospective Validation of Adaptive Radiotherapy (ART) in Patients With Head and Neck Tumors

Condition: Head and Neck Cancer · Adaptive Radiotherapy · Radiation  ·  Sponsor: University Hospital, Essen

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
WhereEssen, Germany / NRW, Germany

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

Adaptive radiotherapy (ART) includes image-guided radiotherapy (IGRT) and also offers further possibilities for plan adaptation. A particularly high benefit can be expected for patients in whom the clinical target volume (CTV) can show a significant change in shape from fraction to fraction due to anatomical deviations. The shape and position constancy of the CTV during the course of the series is examined in this trial. Dosimetric disadvantages of this type have not been reported so far. The aim of this study is to identify patients who benefit from ART at an early stage and to select them for this method, and then to continue to offer ART to this patient group. If a relevant reduction in the minimum planning target volume (PTV) margins with ART compared to IGRT is demonstrated in this study, patients could be treated with ART.

This description comes directly from the study's public registry record.

Talk to the study team

Maja PD Dr. med. Guberina, PD Dr. med. (MD), specialist  ·  +492017232321  ·  maja.guberina@uk-essen.de

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: 1. ECOG 0-1 2. Histopathology confirmation 3. Compliance 4. Tumor in the head and neck region 5. Indication for radiotherapy Exclusion Criteria: 1\. Pregnancy

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

Department for Radiotherapy, University Hospital Essen, National Center for Tumor Diseases (NCT) WestEssen, Germany / NRW, GermanyRecruiting

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Essen

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