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Study identifier: NCT06166199 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingSLE-HIIT

Effects of High-intensity Interval Training in Patients With Systemic Lupus Erythematosus

Condition: Lupus Erythematosus, Systemic  ·  Sponsor: Karolinska Institutet

PhaseNA
Planned participants40
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
WhereStockholm, Huddinge, Sweden

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

The aim of this study is to evaluate the safety and effects of high-intensity interval training (HIIT) combined with resistance training in patients with systemic lupus erythematosus

This description comes directly from the study's public registry record.

Talk to the study team

Carina M Boström, Dr  ·  046 0722006321  ·  carina.bostrom@ki.se

Ioannis Parodis, Dr  ·  046 0722321322  ·  ioannis.parodis@ki.se

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * ≥18 years old * Fulfilment of the 1982 American College of Rheumatology (ACR) criteria; or 2012 Systemic Lupus International Collaborating Clinics (SLICC/ACR-Damage Index (DI)) classification criteria; or EULAR/ACR criteria; or patients that have received the diagnosis SLE on clinical grounds * Low to moderate disease activity, for example defined as a score of ≤5 in the clinical version of the SLE Disease Activity Index 2000 (SLEDAI-2K), i.e., excluding the serological descriptors (anti-dsDNA positivity and low complement levels) * Low/minimal or no organ damage, for example defined as a score of ≤3 in the SLICC/ACR DI * Stable pharmacological treatment * The ability to perform a maximal ergometercycle exercise test * Be able to read and understand Swedish Exclusion Criteria: * Symptoms or signs of cerebro-vascular disease, pulmonary embolus, pulmonary hypertension, pulmonary fibrosis, cardiovascular disease, angina pectoris, myocardial infarction, dyspnea at rest, uncontrolled blood pressure and uncontrolled diabetes within one year prior to study entry. Chronic kidney disease with * Patients who fulfil the absolute contraindications for maximal exercise testing according to American Heart Association * Patients who cannot perform a maximal ergometercycle exercise test due to the disease * Diseases or other conditions that strongly reduce the ability to exercise or that exercise is not recommended * Patients who perform regular aerobic fitness training and muscle strength exercise sessions at fixed times, \>1 time/week * Pregnancy

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

Carina BoströmStockholm, Huddinge, SwedenRecruiting

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Stockholm

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