EICHORCondition: Atrial Fibrillation · Sponsor: Henan Provincial People's Hospital
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The success rate of single-procedure atrial arrhythmia-free survival particularly ranged from 40% to 66% in persistent AF ablation. However, The surgical Cox maze III procedure has been established to be an effective curative strategy for AF with an AF-free survival rate of more than 95%. The main reason is the difficulty of creating continuous, transmural, and durable lesions by catheter ablation, especially when the procedure is performed on some complex anatomical structures in which epicardial muscular bundles may serve as components of the reentrant circuits. The durability of the conduction block is a crucial factor for long-term effective AF ablation since previous studies reported that the reconnected Pulmonary veins contributed to the atrial tachycardia recurrence after persistent AF ablation. In addition, it is possible that the inadequate lesions accidentally produce new arrhythmogenic substrates. Therefore, new and better techniques are always chosen to minimize the reconnection of Pulmonary vein isolation (PVI) and additional ablation. For paroxysmal AF, the ablation strategy of PVI plus superior vena cava isolation is chosen while PVI, superior vena cava isolation, and linear ablation of linear ablations of the mitral isthmus, roofline and posterior wall line of the left atrium, and cavotricuspid isthmus (CTI) for persistent AF. Any symptomatic or asymptomatic atrial arrhythmia lasting more than 30 seconds was regarded as an AF recurrence after a 3-month blank…
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Yingjie Chu · +8613027736160 · hnqbdsl@126.com
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Inclusion Criteria: * Radiofrequency catheter ablation for the first time * AF rhythm recorded by ECG Exclusion Criteria: * Thrombosis in left atrium * Left ventricular ejection fraction of \< 35% * Abnormal thyroid function * Previous history of AF radiofrequency ablation and CABG * Left atrium diameter of \> 65 mm or the volume of \> 200 ml
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| Department of Cardiology, Henan Provincial People's Hospital | Zhengzhou, Henan, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT06145906