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Study identifier: NCT06120881 Synced from ClinicalTrials.gov · August 09, 2026
● Study status: RecruitingPRECISE_T2D

Precision Dosing of Metformin in Youth With T2D

Condition: Type 2 Diabetes  ·  Sponsor: University of California, San Francisco

PhaseEARLY_Phase 1
Planned participants20
Who can joinAll sexes, 10 Years to 21 Years
Healthy volunteersYesCheck eligibility criteria ↓
Where2 locations

Interested? Contact the study team ↓

For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.See where this study is running →

About this study

The purpose of this study to compare the typically prescribed dose of metformin (1000mg twice a day) with a higher dose of metformin (1350mg twice a day).

This description comes directly from the study's public registry record.

Talk to the study team

Avani A Narayan, MS  ·  628-224-8364  ·  avani.narayan@ucsf.edu

Laura A. Dapkus Humphries, NCPT  ·  628-224-8364  ·  laura.dapkus@ucsf.edu

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Age 10-21 years * Provider diagnosis of T2D * Stable medication regimen for 2 weeks before screening visit (No addition or removal of medications and no more than 20% change in insulin dose) * ≥ 1 month from T2D diagnosis * Taking regular metformin (not extended-release formula) * Ability to wear CGM for a total of 6 weeks while in the study. * English or Spanish speakers. * Willing to abide by recommendations and study procedures. * Willing and able to sign the Informed Consent Form (ICF) and/or has a parent or guardian willing and able to sign the ICF. * Participant and parent(s)/guardian(s) willingness to participate in all training sessions as directed by study staff. Written informed consent (and assent when applicable) obtained from subject or subject's legal representative and ability for subject to comply with the requirements of the study. Exclusion Criteria: * Pancreatic autoantibody positivity (GAD-65, insulin, IA-2, ICA 512, Zn-T8). * Known history of ongoing renal or hepatic disease. * Known history of significant mental illness or developmental delay impacting the ability to complete study activities independently.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (2)

UCSF Benioff Children's Hospital Oakland, Pediatric Diabetes ClinicOakland, California, United StatesRecruiting
UCSF Benioff Children's Hospital San Francisco, Madison Clinic for Pediatric DiabetesSan Francisco, California, United StatesRecruiting

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

OaklandSan Francisco

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