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Study identifier: NCT06118281 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Recruiting

ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack

Condition: Cardiovascular Risk · Acute Myocardial Infarction (AMI)  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants10000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting ziltivekimab or placebo is the same. The participant will need to inject the study medicine into a flat skin surface in there stomach, thigh, or upper arm once every month. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study will last for about 2 years.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (970)

Advanced Cardiovascular, LLCAlexander City, Alabama, United StatesActive Not Recruiting
Birmingham VA Medical CenterBirmingham, Alabama, United StatesActive Not Recruiting
Grandview Medical CenterBirmingham, Alabama, United StatesActive Not Recruiting
Eastern Shore Rsrch Inst, LLCFairhope, Alabama, United StatesActive Not Recruiting
Heart Center Rsrch_HunstvilleHuntsville, Alabama, United StatesActive Not Recruiting
Mobile Heart USA Health Cardiology ClinicMobile, Alabama, United StatesCompleted
Mercy Gilbert Medical CenterGilbert, Arizona, United StatesActive Not Recruiting
Mayo Clinic ArizonaPhoenix, Arizona, United StatesActive Not Recruiting
Honor HealthScottsdale, Arizona, United StatesCompleted
Arkansas Cardiology ClinicLittle Rock, Arkansas, United StatesActive Not Recruiting
Central Arkansas Veteran's Healthcare SystemLittle Rock, Arkansas, United StatesNot Yet Recruiting
Valley Clinical TrialsCovina, California, United StatesActive Not Recruiting

+ 958 more locations — full list on the registry record.

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