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Study identifier: NCT06095583 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Phase 3 Study of Toripalimab Alone or in Combination With Tifcemalimab as Consolidation Therapy in Patients With Limited-stage Small Cell Lung Cancer (LS-SCLC)

Condition: Limited-stage Small Cell Lung Cancer (LS-SCLC)  ·  Sponsor: Shanghai Junshi Bioscience Co., Ltd.

PhasePhase 3
Planned participants756
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The Study is a Phase 3, randomized, three-arm, double-blind, placebo-controlled, multi-regional clinical research study to evaluate the safety and efficacy use of toripalimab alone or in combination with tifcemalimab as consolidation therapy in patients with limited-stage small cell lung cancer without disease progression following chemoradiotherapy. Tifcemalimab is a monoclonal antibody against B and T lymphocyte attenuator (BTLA). Toripalimab is a monoclonal antibody against programmed death protein-1 (PD-1). Neither drug is approved for treatment of This combination regimen is investigational in limited stage-small cell lung cancer in any country.

This description comes directly from the study's public registry record.

Talk to the study team

kui zhang, Project Directer  ·  08618168028925  ·  kui_zhang@junshipharma.com

Kinga Kovacs, Senior Project Leader  ·  + 31 6 45974346  ·  Kinga.Kovacs@parexel.com

Always discuss trial participation with your own doctor first.

Locations (76)

Harbin Medical University Cancer HospitalHarbin, Heilongjiang, ChinaRecruiting
Xiangya Hospital Central South UniversityChangsha, Hunan, ChinaRecruiting
The Second Affiliated Hospital of Nanchang UniversityNanchang, Jiangxi, ChinaRecruiting
The First Hospital of China Medical UniversityShenyang, Liaoning, ChinaRecruiting
Shandong Cancer Hospital & InstituteJinan, Shandong, ChinaRecruiting
Anyang Tumor HospitalAnyang, ChinaRecruiting
Beijing Cancer HospitalBeijing, ChinaNot Yet Recruiting
Cancer Hospital Chinese Academy of Medical SciencesBeijing, ChinaRecruiting
Jilin Cancer HospitalChangchun, ChinaRecruiting
Hunan Cancer HospitalChangsha, ChinaRecruiting
Sichuan cancer hospitalChengdu, ChinaNot Yet Recruiting
Chongqing University Cancer HospitalChongqing, ChinaRecruiting

+ 64 more locations — full list on the registry record.

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