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Study identifier: NCT05996471 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

A Study to Investigate the Virologic Efficacy and Safety of VH3810109 + Cabotegravir Compared to Standard of Care (SOC) in Male and Female Adults Living With Human Immunodeficiency Virus (HIV)

Condition: HIV Infections  ·  Sponsor: ViiV Healthcare

PhasePhase 2
Planned participants185
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The study aims at evaluating the efficacy of VH3810109, dosed in accordance with the dosing schedule as either intravenous (IV) infusion or subcutaneous (SC) infusion with recombinant hyaluronidase (rHuPH20), in combination with cabotegravir (CAB) intramuscular (IM) dosed in accordance with the dosing schedule in virologically suppressed, Antiretroviral therapy (ART)-experienced adult participants living with HIV. VH3810109 plus rHuPH20 plus Cabotegravir arm of the study has been discontinued based on preliminary results. The study will be conducted in 3 parts followed by a Long-Term Follow-up phase (LTFU).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (45)

GSK Investigational SiteBirmingham, Alabama, United States
GSK Investigational SiteBakersfield, California, United States
GSK Investigational SiteLos Angeles, California, United States
GSK Investigational SiteLos Angeles, California, United States
GSK Investigational SitePalm Springs, California, United States
GSK Investigational SiteSacramento, California, United States
GSK Investigational SiteSan Francisco, California, United States
GSK Investigational SiteNew Haven, Connecticut, United States
GSK Investigational SiteWashington D.C., District of Columbia, United States
GSK Investigational SiteWashington D.C., District of Columbia, United States
GSK Investigational SiteFort Lauderdale, Florida, United States
GSK Investigational SiteFt. Pierce, Florida, United States

+ 33 more locations — full list on the registry record.

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