EICHORCondition: Atopic Dermatitis · Sponsor: Pfizer
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The purpose of this study is to learn about the safety and effects of 2 study medicines (PF-07275315 and PF-07264660) for the treatment of atopic dermatitis (AD). AD is a long- lasting itchy red rash, caused by a skin reaction. This study is seeking participants who: * are 18 years of age or more. * Were confirmed to have AD at least 6 months ago. * Are not having an effective treatment result from medicines that are applied on skin for AD. * Are considered by their doctors to have moderate to severe AD. In Stage 1 of the study, participants will receive either PF-07275315 or PF-07264660 or placebo. Stage 1 is complete. In Stage 2 of the study participants will receive either PF-07275315 or placebo. In Stage 3 of the study participants who have received anti-inflammatory proteins, will receive either PF-07275315 or placebo. In Stage 4 of the study participants will receive either PF-07264660 or placebo. A placebo does not have any medicine in it but looks just like the medicines being studied. PF-07275315 or PF-07264660 or placebo will be given as multiple shots in the clinic over the course of each Stage. The experiences of people receiving PF-07275315 or PF-07264660 will be compared to people who do not. This will help determine if PF-07275315 and PF-07264660 are safe and effective. Participants in Stages 1, 2 and 4 will be involved in this study for up to 40 weeks (10 months). Participants in Stage 3 will be involved in this study for up to 52 weeks (13 months).
This description comes directly from the study's public registry record.
Pfizer CT.gov Call Center · 1-800-718-1021 · ClinicalTrials.gov_Inquiries@pfizer.com
Always discuss trial participation with your own doctor first.
| Allervie Clinical Research | Birmingham, Alabama, United States | Recruiting |
| Onyx Clinical Research - Peoria | Peoria, Arizona, United States | Recruiting |
| Medical Dermatology Specialists | Phoenix, Arizona, United States | Recruiting |
| Onyx Clinical Research | Phoenix, Arizona, United States | Recruiting |
| Banner - University Medicine Dermatology Clinic | Tucson, Arizona, United States | Recruiting |
| Marvel Clinical Research | Huntington Beach, California, United States | Recruiting |
| California Allergy and Asthma Medical Group | Los Angeles, California, United States | Recruiting |
| University Dermatology Trials, INC. | Newport Beach, California, United States | Recruiting |
| Northridge Clinical Trials | Northridge, California, United States | Recruiting |
| Profound Research LLC | Oceanside, California, United States | Recruiting |
| Dermatology Cosmetic Laser Medical Associates of La Jolla, Inc. | San Diego, California, United States | Recruiting |
| West Dermatology La Jolla | San Diego, California, United States | Recruiting |
+ 86 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT05995964