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Study identifier: NCT05977803 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingACROP

Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin

Condition: Brain Metastases · Radionecrosis · Pulmonary Cancer  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
WhereParis, France

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The aim of the study is to determine whether the use of the CEST sequence would have diagnostic performance equivalent to the reference method of T2\* infusion with contrast injection in the diagnosis of radionecrosis of lung cancer brain metastases.

This description comes directly from the study's public registry record.

Talk to the study team

Augustin Gaudemer, MD  ·  01 40 25 76 13  ·  augustin.gaudemer@aphp.fr

Marie-Cécile Henry-Feugeas, MD  ·  01 40 25 81 52  ·  marie-cecile.henry-feugeas@aphp.fr

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Patients \> 18 years of age * Histologically proven primary lung cancer * Histologically proven or not brain metastases * Irradiated metastases * Inclusion in a treatment protocol for brain metastases by brain metastasis in toto or stereotactic or gamma-knife radiotherapy * Morphological increase of one or more lesions of secondary brain metastases on a follow-up MRI * Patients affiliated to a social security scheme Exclusion Criteria: * Opposition to the study * Contraindication to MRI * Refusal of imaging by the patient * Patient with state medical aid (unless exemption from affiliation) * Severe cognitive impairment making informed consent impossible * Patients under guardianship or deprived of liberty

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

Hôpital Bichat-Claude BernardParis, FranceRecruiting

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Paris

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