Condition: Type 2 Diabetes · Sponsor: Eli Lilly and Company
Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
The main purpose of this study is to determine safety and efficacy of orforglipron compared with placebo in adult participants with type 2 diabetes and inadequate glycemic control with diet and exercise alone. The study will last approximately 54 weeks.
This description comes directly from the study's public registry record.
No contact information is available for this study as per the public registry record.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Have Type 2 Diabetes * Have HbA1c ≥7.0% (53 mmol/mol) to ≤9.5% (80 mmol/mol) despite diet and exercise treatment, as determined by the central laboratory at screening. * Are naïve to insulin therapy except for gestational diabetes or ≤14 days use for acute treatment and have not used any oral or injectable antihyperglycemic medications during the 90 days preceding screening or between screening and randomization. * Are of stable weight (±5%) for at least 90 days prior to screening and agree to not initiate an intensive diet or exercise program during the study with the intent of reducing body weight other than the lifestyle and/or dietary measures for diabetes treatment. * Have a body mass index (BMI) ≥23.0 kilogram/square meter (kg/m²) at screening. Exclusion Criteria: * Have Type 1 Diabetes * Have a history of ketoacidosis or hyperosmolar state or coma within the last 6 months prior to screening, or between screening and randomization. * Currently receiving or planning to receive treatment for diabetic retinopathy and/or macular edema * Have New York Heart Association functional classification IV congestive heart failure. * Have acute or chronic pancreatitis
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Syed Research Consultants Llc | Sheffield, Alabama, United States | — |
| Epic Medical Research - Surprise | Surprise, Arizona, United States | — |
| Quality of Life Medical & Research Center | Tucson, Arizona, United States | — |
| Neighborhood Healthcare Institute of Health | Escondido, California, United States | — |
| Velocity Clinical Research, Huntington Park | Huntington Park, California, United States | — |
| Ark Clinical Research | Long Beach, California, United States | — |
| Velocity Clinical Research, Westlake | Los Angeles, California, United States | — |
| Infinity Clinical Research - Norco | Norco, California, United States | — |
| Norcal Endocrinology & Internal Medicine | San Ramon, California, United States | — |
| University Clinical Investigators, Inc. | Tustin, California, United States | — |
| Connecticut Clinical Research - Cromwell | Cromwell, Connecticut, United States | — |
| Invictus Clinical Research Group | Coconut Creek, Florida, United States | — |
+ 77 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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