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Study identifier: NCT05957081 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Study to Assess the Safety, Tolerability, and Blood Concentration of PMC-309

Condition: Advanced or Metastatic Solid Tumors  ·  Sponsor: PharmAbcine

PhasePhase 1
Planned participants67
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This is a Phase 1a/1b, first-in-human (FIH), open label study to evaluate the safety, tolerability, and pharmacokinetics (PK) of PMC-309, a mAb against the human VISTA ligand, in participants with advanced or metastatic solid tumors administered as a monotherapy and in combination with pembrolizumab.

This description comes directly from the study's public registry record.

Talk to the study team

Hyojin Koh, Dr  ·  070-4213-2925  ·  hyojin.koh@pharmabcine.com

Always discuss trial participation with your own doctor first.

Locations (4)

Australian Hospital Care (Pindara) PTY LTD. Trading as Pindara Private HospitalBenowa, Queensland, AustraliaRecruiting
Ballarat Regional Integrated Cancer Centre (Grampians Health)Ballarat, Victoria, AustraliaRecruiting
Cabrini Health LimitedMalvern, Victoria, AustraliaRecruiting
Alfred HealthMelbourne, Victoria, AustraliaRecruiting

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