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Study identifier: NCT05952856 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids

Condition: Hypercholesterolemia · Familial Hypercholesterolemia  ·  Sponsor: Merck Sharp & Dohme LLC

PhasePhase 3
Planned participants2912
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this study is to evaluate the efficacy, safety, and tolerability of enlicitide decanoate in adult participants with hypercholesterolemia. The primary hypothesis is that enlicitide decanoate is superior to placebo on mean percent change from baseline in low-density lipoprotein cholesterol (LDL-C) at Week 24.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (168)

Alliance for Multispecialty Research, LLC ( Site 0093)Daphne, Alabama, United States
G&L Research ( Site 0043)Foley, Alabama, United States
Synexus Clinical Research US, Inc.-Synexus Clinical Research US, Inc - Central Phoenix ( Site 0084)Phoenix, Arizona, United States
National Heart Institute-Research ( Site 0087)Beverly Hills, California, United States
Clinical Trials Research ( Site 0115)Sacramento, California, United States
Velocity Clinical Research, Banning ( Site 0017)San Bernardino, California, United States
Emerson Clinical Research Institute ( Site 0118)Washington D.C., District of Columbia, United States
Excel Medical Clinical Trials ( Site 0053)Boca Raton, Florida, United States
Alliance for Multispecialty Research, LLC ( Site 0088)Coral Gables, Florida, United States
Alliance for Multispecialty Research, LLC ( Site 0094)Fort Myers, Florida, United States
Velocity Clinical Research, Hallandale Beach ( Site 0018)Hallandale, Florida, United States
Jacksonville Center for Clinical Research ( Site 0049)Jacksonville, Florida, United States

+ 156 more locations — full list on the registry record.

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