EICHORCondition: Leukemia, Lymphocytic, Chronic, B-Cell · Leukemia, Chronic Lymphocytic · Small-Cell Lymphoma · Sponsor: Merck Sharp & Dohme LLC
The purpose of this study is to assess the safety and tolerability and to confirm the dose of nemtabrutinib in combination with venetoclax in participants with R/R CLL/SLL. The primary study hypotheses are that the combination of nemtabrutinib plus venetoclax is superior to VR with respect to progression-free survival (PFS) per 2018 International Workshop on Chronic Lymphocytic Leukemia (iwCLL) criteria as assessed by blinded independent central review (BICR).
This description comes directly from the study's public registry record.
Toll Free Number · 1-888-577-8839 · Trialsites@msd.com
Always discuss trial participation with your own doctor first.
| Highlands Oncology Group ( Site 5405) | Springdale, Arkansas, United States | Recruiting |
| MemorialCare Health System - Long Beach Medical Center ( Site 5421) | Long Beach, California, United States | Recruiting |
| Memorial Hospital West ( Site 5410) | Pembroke Pines, Florida, United States | Recruiting |
| Oregon Health and Science University ( Site 5425) | Portland, Oregon, United States | Recruiting |
| Medical Oncology Associates, PS ( Site 5406) | Spokane, Washington, United States | Recruiting |
| University of Wisconsin Hospital and Clinics-Carbone Cancer Center ( Site 5423) | Madison, Wisconsin, United States | Completed |
| Instituto Alexander Fleming ( Site 1005) | Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina | Recruiting |
| Instituto de Investigaciones Clínicas Mar del Plata ( Site 1007) | Mar del Plata, Buenos Aires, Argentina | Recruiting |
| Centro de Educación Médica e Investigaciones Clínicas (CEMIC)-Hematology ( Site 1002) | Buenos Aires, Buenos Aires F.D., Argentina | Recruiting |
| Sanatorio Parque ( Site 1003) | Rosario, Santa Fe Province, Argentina | Recruiting |
| Centro Medico Fleischer ( Site 1006) | Buenos Aires, Argentina | Recruiting |
| Hospital Aleman-oncohematologic diseases ( Site 1001) | Buenos Aires, Argentina | Recruiting |
+ 43 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05947851