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Study identifier: NCT05941741 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

IC Plus Low-dose Radiation Plus Cadonilimab in LANPC

Condition: Nasopharyngeal Carcinoma · Immune Checkpoint Inhibitor · Radiotherapy  ·  Sponsor: Sun Yat-sen University

PhasePhase 3
Planned participants380
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

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About this study

This is a multi-center, open-label, randomized controlled phase III clinical trial in primary diagnosed loco-regionally advanced nasopharyngeal carcinoma (NPC) patients. The purpose of this study is to evaluate the efficacy of induction chemotherapy (IC) combined with low-dose radiation and immune checkpoint inhibitor (ICI) followed by concurrent chemoradiotherapy (CCRT) versus IC+CCRT, and compare the treatment-related adverse events and quality of life in two groups.

This description comes directly from the study's public registry record.

Talk to the study team

Chong Zhao, MD, PhD  ·  02087342638  ·  zhaochong@sysucc.org.cn

Jingjing Miao, MD  ·  +8613631355201  ·  miaojj@sysucc.org.cn

Always discuss trial participation with your own doctor first.

Locations (3)

Cancer Center, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting
The First Affiliated Hospital of Guangxi Medical UniversityNanning, Guangxi, ChinaNot Yet Recruiting
Jiangxi Cancer HospitalNanchang, Jiangxi, ChinaNot Yet Recruiting

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