EICHORCondition: Major Depressive Disorder · Sponsor: Alto Neuroscience
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Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics.
This description comes directly from the study's public registry record.
Alto Neuroscience · 650-200-0412 · clinical@altoneuroscience.com
There is no obligation to join — the study team can answer your questions about taking part.
Always discuss trial participation with your own doctor first.
Inclusion Criteria: * Have a diagnosis of moderate to severe major depressive disorder (MDD) * At Visit 1, currently taking a single SSRI, SNRI, or bupropion for at least 6 weeks with no dose modifications in the past 2 weeks by Visit 2 * Willing to comply with all study assessments and procedures * Must not be pregnant or breastfeeding at time of enrollment or throughout study Exclusion Criteria: * Evidence of unstable medical condition * Nightly use of sleep medication * Diagnosed bipolar disorder, psychotic disorder, or dementia * Current moderate or severe substance use disorder * Has a history of hypersensitivity or allergic reaction to ALTO-300 or any of its components/excipients * Concurrent or recent participation in another clinical trial for mental illness involving an investigational product or device
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| Site 200 | Phoenix, Arizona, United States | Recruiting |
| Site 189 | Phoenix, Arizona, United States | Withdrawn |
| Site 187 | Yuma, Arizona, United States | Recruiting |
| Site 193 | Rogers, Arkansas, United States | Recruiting |
| Site 218 | Bellflower, California, United States | Recruiting |
| Site 217 | Glendale, California, United States | Recruiting |
| Site 335 | Lafayette, California, United States | Recruiting |
| Site 209 | Los Angeles, California, United States | Recruiting |
| Site 219 | Mather, California, United States | Recruiting |
| Site 194 | Mission Viejo, California, United States | Recruiting |
| Site 197 | Temecula, California, United States | Recruiting |
| Site 203 | Colorado Springs, Colorado, United States | Recruiting |
+ 33 more locations — full list on the registry record.
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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Source record: clinicaltrials.gov/study/NCT05922878