EICHORCondition: Alveolar Bone Resorption · Sponsor: Second Affiliated Hospital, Zhejiang University, School of Medicine
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In this experiment, after non-traumatic tooth extraction, the blank group underwent natural healing, and the Bio-Oss Collagen underwent alveolar ridge preservation using Bio-Oss Collagen and the Sticky Bone group using Sticky Bone, to verify the application of Bio-Oss Collagen and Sticky Bone in alveolar ridge preservation
This description comes directly from the study's public registry record.
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Inclusion Criteria: 1. The presence of one adjacent tooth at the extraction site 2. Adequate oral hygiene (plaque index \<20%;bleeding on probing \<25% ) 3. Need for tooth extraction due to endodontic，periapical or periodontal disease. 4. Presence of ≥ 2 mm of keratinized tissue 5. the extraction sockets have no more than 50% of buccal alveolar bone loss(Integrity of alveolar bone walls) Exclusion Criteria: 1. Pregnancy or lactation 2. Smoking more than 10 cigarettes per day 3. with no evidence of acute infection such as severe swelling, suppuration at the extraction site 4. Uncontrolled periodontal disease 5. Existence of bone metabolic disease 6. history of malignancy, radiotherapy, or chemotherapy in the past 5 years 7. Administration of bisphosphonates 8. long-term use of NSAIDs 9. Alcohol or drug abuse 10. Infectious disease, such as hepatitis or human immunodeficiency virus (HIV) and/or acquired immunodeficiency syndrome (AIDS) 11. Uncontrolled severe diabetes.( hemoglobin A1c \>6.7%)
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| 2nd Affiliated Hospital, School of Medicine, Zhejiang University, China | Hangzhou, Zhejiang, China | — |
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Source record: clinicaltrials.gov/study/NCT05902689