EICHORCondition: Head and Neck Cancer · Sponsor: Royal Marsden NHS Foundation Trust
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The RESCUE study is a combined retrospective and prospective multicentre cohort study investigating the survival and functional outcomes in patients undergoing salvage surgery for recurrent, residual, and new primary head and neck squamous cell carcinoma (SCC). Additionally, the RESCUE study will contain an exploratory molecular analysis of consenting patients to assess the relationship between cancer genomics, previous radiotherapy, and recurrence in head and neck cancer.
This description comes directly from the study's public registry record.
Andrew Williamson · 02073528171 · andrew.williamson2@rmh.nhs.uk
Sarah Burton · 02073528171 · RESCUE@rmh.nhs.uk
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Inclusion Criteria: 1. Aged over 18 2. Previous H\&N SCC treated with radiotherapy with or without chemotherapy 3. Local or regionally recurrent, residual, or new primary SCC of the oropharynx, oral cavity, larynx, and hypopharynx 4. Ability to give informed consent for biological sample collection (molecular analysis study only) Exclusion Criteria: 1. Nasopharyngeal and cutaneous SCC of the H\&N 2. Thyroid, salivary gland, and non-squamous cell H\&N cancers 3. Presence of distant metastasis (M1) or surgically inoperable T4b tumours
Reproduced word-for-word from the public registry record — the study team can answer questions about it.
| University Hospitals Derby and Burton | Derby, United Kingdom | Recruiting |
| NHS Lothian | Edinburgh, United Kingdom | Recruiting |
| Western General, Greater Glasgow and Clyde | Glasgow, United Kingdom | Recruiting |
| Aintree Hospital | Liverpool, United Kingdom | Recruiting |
| Head and Neck Unit, Royal Marsden Hospital | London, United Kingdom | Recruiting |
| Northwick Park | London, United Kingdom | Recruiting |
| Oxford University Hospital NHS Foundation Trust | Oxford, United Kingdom | Recruiting |
| Poole Hospital, University Hospitals Dorset | Poole, United Kingdom | Recruiting |
| South Tyneside and Sunderland NHS Foundation Trust | Sunderland, United Kingdom | Completed |
This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.
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Source record: clinicaltrials.gov/study/NCT05808920