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Study identifier: NCT05775965 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

HIP Fracture Oral ThromboPROphylaxis (Hip PRO Pilot)

Condition: Hip Fractures  ·  Sponsor: University of Calgary

PhasePhase 2
Planned participants250
Who can joinAll sexes, 50 Years to no upper limit
Healthy volunteersNo

About this study

As our Canadian population ages, hip fractures in these older adults are becoming very common. The best treatment for the majority of these injuries is urgent treatment with surgery. However, the hip fracture itself, the surgery required, and the immobility following these injuries are all risk factors for developing blood clots in the legs (deep vein thrombosis or DVT) and blood clots in the lungs (pulmonary embolism or PE). These complications are a common cause of death in patients with hip fractures and often result in prolonged medical treatment and hospital stays. Patients with hip fractures who require surgery are traditionally given injectable blood thinners to help prevent blood clots; however, these medications are costly, may not be tolerated well, and can be difficult to take, as prescribed. Oral blood thinning medications are being used more commonly, but it is unknown which of these medications is the most effective in preventing blood clots in patients after a hip fracture. Thrombelastography (TEG) technology uses a small sample of blood to evaluate a person's clotting ability. Our research has used TEG technology to evaluate blood clotting risk after hip fracture surgery and the investigators have found that platelets may play an important role in abnormal blood clotting after a hip fracture. The investigators have also shown that acetylsalicylic acid (ASA or Aspirin) may help reduce the abnormal platelet hyperactivity associated with blood clotting. This me…

This description comes directly from the study's public registry record.

Talk to the study team

Prism S Schneider, MD, PhD  ·  (403) 944-4518  ·  prism.schneider@albertahealthservices.ca

Jessica Duong, PhD  ·  (403) 220-3366  ·  jduong@ucalgary.ca

Always discuss trial participation with your own doctor first.

Locations (3)

Foothills Medical CentreCalgary, Alberta, CanadaRecruiting
Royal Columbian HospitalNew Westminster, British Colombia, CanadaNot Yet Recruiting
The Ottawa HospitalOttawa, Ontario, CanadaNot Yet Recruiting

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