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Study identifier: NCT05680818 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

Efficacy and Safety of Encaleret Compared to Standard of Care in Participants With ADH1

Condition: Autosomal Dominant Hypocalcemia (ADH)  ·  Sponsor: Calcilytix Therapeutics, Inc., a BridgeBio company

PhasePhase 3
Planned participants67
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersNo

About this study

The primary purpose of the study is to understand the effectiveness, safety, and tolerability of encaleret when compared to standard of care (SoC) treatment in participants with Autosomal Dominant Hypocalcemia Type 1 (ADH1).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (25)

UCSF Benioff Children's Hospital, OaklandOakland, California, United States
Children's Hospital ColoradoAurora, Colorado, United States
Indiana University Health University HospitalIndianapolis, Indiana, United States
NIHBethesda, Maryland, United States
Massachusetts General HospitalBoston, Massachusetts, United States
Mayo Clinic - RochesterRochester, Minnesota, United States
Columbia University Irving Medical CenterNew York, New York, United States
Physicians EastGreenville, North Carolina, United States
Ohio State University Medical CenterColumbus, Ohio, United States
The Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United States
Houston Methodist HospitalHouston, Texas, United States
Royal North Shore HospitalSaint Leonards, New South Wales, Australia

+ 13 more locations — full list on the registry record.

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