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Study identifier: NCT05651711 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

A Study Assessing Rocatinlimab (AMG 451) Monotherapy in Moderate-to-severe Atopic Dermatitis (AD) (ROCKET-Horizon)

Condition: Atopic Dermatitis  ·  Sponsor: Amgen

PhasePhase 3
Planned participants726
Who can joinAll sexes, 18 Years to 100 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The co-primary objectives of the study are to: * Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed using Validated Investigator's Global Assessment for Atopic Dermatitis (vIGA-AD). * Evaluate the efficacy of rocatinlimab compared with placebo at Week 24, assessed using Eczema Area and Severity Index (EASI).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (197)

Research Solutions of Arizona, PCLitchfield Park, Arizona, United States
Center for Dermatology and Plastic SurgeryScottsdale, Arizona, United States
Clinical Trials Institute of Northwest ArkansasFayetteville, Arkansas, United States
Burke Pharmaceutical ResearchHot Springs, Arkansas, United States
Velocity Clinical Research Chula VistaChula Vista, California, United States
West Coast Research LLCDublin, California, United States
California Dermatology and Clinical Research InstituteEncinitas, California, United States
Center for Dermatology Clinical Research IncFremont, California, United States
Velocity Clinical Research - San DiegoLa Mesa, California, United States
Velocity Clinical Research - North HollywoodNorth Hollywood, California, United States
Cura Clinical ResearchPalmdale, California, United States
University of California at San Francisco, Dermatology Clinic at Mount ZionSan Francisco, California, United States

+ 185 more locations — full list on the registry record.

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