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Study identifier: NCT05639114 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Active Not Recruiting

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

Condition: Systemic Lupus Erythematosus  ·  Sponsor: Novartis Pharmaceuticals

PhasePhase 3
Planned participants436
Who can joinAll sexes, 12 Years to 100 Years
Healthy volunteersNo

About this study

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (s.c.) injection on top of standard-of-care (SoC) treatment in participants with active systemic lupus erythematosus (SLE).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (135)

Pinnacle Research Group LlcAnniston, Alabama, United States
Providence Medical CenterBurbank, California, United States
University of California San DiegoLa Jolla, California, United States
Millennium Clinical TrialsWestlake Village, California, United States
University of ColoradoAurora, Colorado, United States
Yale University School Of MedicineNew Haven, Connecticut, United States
Clinical Res Of W FloridaClearwater, Florida, United States
GNP ResearchCooper City, Florida, United States
Clinical Research of West Florida IncTampa, Florida, United States
Parris and Associates RheumatologyLawrenceville, Georgia, United States
Chicago Clinical Research InstChicago, Illinois, United States
Robert A Hozman MD SCSkokie, Illinois, United States

+ 123 more locations — full list on the registry record.

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