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Study identifier: NCT05535933 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

HMPL-523 (Sovleplenib) in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia

Condition: Warm Antibody Autoimmune Hemolytic Anemia  ·  Sponsor: Hutchmed

PhasePhase 2/Phase 3
Planned participants111
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

Phase II Study: To evaluate the safety and preliminary efficacy of HMPL-523 in adult patients with wAIHA. Phase III Study(Part A): Confirmation of Efficacy safety and of HMPL-523 in adult patients with wAIHA. Phase III Study (Part B): To further evaluate the long-term safety and tolerability of HMPL-523 in adult patients with wAIHA.

This description comes directly from the study's public registry record.

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Locations (39)

Fuyang Hospital Of Anhui Medical UniversityFuyang, Anhui, China
Fujian Medical University Union HospitalFuzhou, Fujian, China
Lanzhou University Second HospitalLanzhou, Gansu, China
Nanfang hospitalGuangzhou, Guangdong, China
Shenzhen Second People's HospitalShenzhen, Guangdong, China
Affiliated Hospital of Guangdong Medical UniversityZhanjiang, Guangdong, China
Guilin Medical College Affiliated HospitalGuilin, Guangxi, China
Hainan General HospitalHaikou, Hainan, China
Affiliated hospital of Hebei universityBaoding, Hebei, China
Affiliated hospital of chengde medical universityChengde, Hebei, China
Harbin First HospitalHarbin, Heilongjiang, China
The First Affiliated Hospital of Henan University Of Science and TechnologyLuoyang, Henan, China

+ 27 more locations — full list on the registry record.

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