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Study identifier: NCT05486416 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery

Condition: General Anesthesia  ·  Sponsor: Haisco-USA Pharmaceuticals, Inc.

PhasePhase 3
Planned participants465
Who can joinAll sexes, 18 Years to 99 Years
Healthy volunteersYes

About this study

To demonstrate HSK3486 0.4/0.2 mg/kg (0.4 mg/kg intravenous \[IV\] slow injection over 30 \[±5\] seconds for the first dose, an additional 0.2 mg/kg if needed) is non-inferior to Propofol 2.0/1.0 mg/kg (2.0 mg/kg IV slow injection over 30 \[±5\] seconds for first dose, an additional 1.0 mg/kg if needed) in success of induction of general anesthesia in adults undergoing elective surgery.

This description comes directly from the study's public registry record.

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Locations (28)

North Alabama Medical CenterFlorence, Alabama, United States
Helen Keller HospitalSheffield, Alabama, United States
University of Miami HospitalMiami, Florida, United States
Gulfcoast Research InstituteSarasota, Florida, United States
Phoenix Clinical Research, LLCTamarac, Florida, United States
ForCare Clinical ResearchTampa, Florida, United States
Atlanta Center for Medical ResearchAtlanta, Georgia, United States
EBGS Clinical Research CenterSnellville, Georgia, United States
University of Iowa Hospitals and Clinics (Dept of Anesthesia)Iowa City, Iowa, United States
U of L Health, University of Louisville HospitalLouisville, Kentucky, United States
The Brigham and Women's HospitalBoston, Massachusetts, United States
Michigan MedicineAnn Arbor, Michigan, United States

+ 16 more locations — full list on the registry record.

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