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Study identifier: NCT05482568 Synced from ClinicalTrials.gov · August 05, 2026
● Study status: Recruiting

A Trial of Injectable SHR-A1811 in Combination With Pyrotinib or SHR-1316 in Subjects With Advanced Non-small Cell Lung Cancer

Condition: Advanced Non-small Cell Lung Cancer  ·  Sponsor: Jiangsu HengRui Medicine Co., Ltd.

PhasePhase 1/Phase 2
Planned participants324
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This study was an open, multicenter, dose-increasing/investigational Phase IB/II clinical trial to evaluate the efficacy of SHR-A1811 in combination with other antitumor therapies in subjects with advanced non-small cell lung cancer with HER2 . It can be divided into two parts, Part A is the dose escalation and efficacy exploration study of SHR-A1811 combined with Pyrotinib, and Part B is the dose escalation and efficacy exploration study of SHR-A1811 combined with SHR-1316.

This description comes directly from the study's public registry record.

Talk to the study team

Suqiang Yu  ·  +0518-82342973  ·  suqiang.yu@hengrui.com

Always discuss trial participation with your own doctor first.

Locations (2)

Shanghai Chest hospitalShanghai, Shanghai Municipality, ChinaRecruiting
Zhejiang Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting

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