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Study identifier: NCT05468736 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Completed

Study to Evaluate Safety and Immunogenicity of COVID-19 Vaccine in Children 6 Months to < 12 Years

Condition: COVID-19  ·  Sponsor: Novavax

PhasePhase 2/Phase 3
Planned participants3600
Who can joinAll sexes, 6 Months to 11 Years
Healthy volunteersYes

About this study

This is a Phase 2/3 randomized, observer-blinded, placebo-controlled, age de-escalation trial to evaluate the safety and immunogenicity of 2 primary doses of SARS-CoV-2 rS with Matrix-M™ adjuvant (NVX-CoV2373) given 21 days apart and NVX CoV2373 or a variant-based vaccine given as a booster dose or at crossover in pediatric participants (3 age cohorts; 6 to \< 12 years, 2 to \< 6 years, and 6 to \< 24 months of age). Each age cohort will be conducted in 2 parts starting with the oldest age cohort (6 to \< 12 years of age).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (94)

Preferred Research Partners, Inc.Little Rock, Arkansas, United States
Advanced Research CenterAnaheim, California, United States
Coast Clinical Research, LLCBellflower, California, United States
Apex Research GroupFair Oaks, California, United States
Ark Clinical ResearchLong Beach, California, United States
Orange County Research InstituteOntario, California, United States
California Research FoundationSan Diego, California, United States
Clinical Research of CaliforniaWalnut Creek, California, United States
Imagine Research of Palm Beach CountyBoynton Beach, Florida, United States
Palm Harbor Dermatology PABrandon, Florida, United States
Westside Center for Clinical ResearchJacksonville, Florida, United States
Cordova Research Institute, LLCMiami, Florida, United States

+ 82 more locations — full list on the registry record.

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