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Study identifier: NCT05446298 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

ONC-392 and Pembrolizumab in Platinum Resistant Ovarian Cancer

Condition: Ovarian Cancer · High Grade Serous Adenocarcinoma of Ovary · Primary Peritoneal Carcinoma  ·  Sponsor: OncoC4, Inc.

PhasePhase 2
Planned participants58
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a study to test the safety and efficacy with the combination of a next generation anti-CTLA-4 antibody, ONC-392, and anti-PD-1 antibody, pembrolizumab, in platinum resistant ovarian cancer patients.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (21)

Cancer Treatment Centers of America, Phoenix. 403Goodyear, Arizona, United States
Honor Health, USOR, 406Phoenix, Arizona, United States
Nuvance Health System, 401Danbury, Connecticut, United States
Baptist MD Anderson Cancer Center, 404Jacksonville, Florida, United States
Sudarshan Sharma, MD. LTD. 414Hinsdale, Illinois, United States
Cancer Treatment Centers of America, Chicago. 410Zion, Illinois, United States
Northwest Cancer Centers - Dyer, IN - USOR, 422Dyer, Indiana, United States
Baptist Health Lexington, 407Lexington, Kentucky, United States
Norton Cancer Institute - St. Matthews, 416Louisville, Kentucky, United States
Willis-Knighton Physician Network / Gynecologic Oncology Associates, 409Shreveport, Louisiana, United States
Minnesota Oncology Hematology, P. A. - USOR, 421Maplewood, Minnesota, United States
Center of Hope, 413Reno, Nevada, United States

+ 9 more locations — full list on the registry record.

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