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Study identifier: NCT05387707 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Terminated

Study to Evaluate the Efficacy and Safety of Oral Difelikefalin as Adjunct Therapy to a Topical Corticosteroid for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis

Condition: Pruritus · Atopic Dermatitis  ·  Sponsor: Cara Therapeutics, Inc.

PhasePhase 3
Planned participants287
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This is a two-part, multicenter, randomized, double-blind study to evaluate the efficacy and safety of oral difelikefalin as adjunct therapy to a topical corticosteroid (TCS) for moderate-to-severe pruritus in adult subjects with atopic dermatitis (AD).

This description comes directly from the study's public registry record.

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No contact information is available for this study as per the public registry record.

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Locations (61)

Cara Therapeutics Study SiteScottsdale, Arizona, United States
Cara Therapeutics Study SiteFort Smith, Arkansas, United States
Cara Therapeutics Study SiteRogers, Arkansas, United States
Cara Therapeutics Study SiteFountain Valley, California, United States
Cara Therapeutics Study SiteLomita, California, United States
Cara Therapeutics Study SiteLos Angeles, California, United States
Cara Therapeutics Study SiteRedwood City, California, United States
Cara Therapeutics Study SiteSacramento, California, United States
Cara Therapeutics Study SiteSan Diego, California, United States
Cara Therapeutics Study Site 2Santa Monica, California, United States
Cara Therapeutics Study SiteSanta Monica, California, United States
Cara Therapeutics Study SiteValencia, California, United States

+ 49 more locations — full list on the registry record.

Sponsor or site team? See the site landscape for this trial — listed sites, countries, and recruiting-density context.

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