EICHORCondition: Surgery--Complications · Pelvic Cancer · Abdominal Cancer · Sponsor: University Hospital Southampton NHS Foundation Trust
Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
Advanced pelvic cancers are uncommon, with treatment being challenging. Around 4000 patients every year need treatment in the UK. Cancers can involve multiple organs and often need radiotherapy and chemotherapy before surgery. Surgery usually requires removal of multiple pelvic organs, including muscles, bone, and skin around the anus (the perineum). This can lead to complications relating to both the empty pelvis syndrome and closure of the perineal defect. Reconstruction is challenging, with frequently occurring complications, reducing speed of recovery and quality of life. This study investigates complication frequency, quality of life and expenses following different reconstruction techniques. The investigators hope to improve patient and doctor decision-making in this area and find the best methods of reconstruction to improve outcomes. REMACS has three work packages: 1. Maintenance of a database of patients undergoing colorectal surgery at Southampton and Salisbury Hospitals, including those undergoing extra-levator abdominoperineal excision and pelvic exenteration. This includes all routinely collected clinical data, imaging, health resource use, and patient reported outcome measures. 2. A collaborative national prospective cohort study investigating morbidity, health resource use, longitudinal quality of life outcomes (EORTC QLQ-C30 and disease-specific modules) and quality adjusted life years. The investigators will also assess financial toxicity using the compreh…
This description comes directly from the study's public registry record.
Charles West, MBBS BSc · +442381208632 · charles.west4@nhs.net
Malcolm West, MD FRCS PhD · malcolm.west@uhs.nhs.uk
Always discuss trial participation with your own doctor first.
| University Hospital Southampton NHS Foundation Trust | Southampton, Hampshire, United Kingdom | Recruiting |
| Salisbury NHS Foundation Trust | Salisbury, Wiltshire, United Kingdom | Recruiting |
| Hampshire Hospitals NHS Foundation Trust | Basingstoke, United Kingdom | Recruiting |
| University Hospitals Sussex NHS Foundation Trust | Brighton, United Kingdom | Not Yet Recruiting |
| Royal Devon University Healthcare NHS Foundation Trust | Cornwell, United Kingdom | Not Yet Recruiting |
| Dorset County Hospital NHS Foundation Trust | Dorchester, United Kingdom | Recruiting |
| NHS Greater Glasgow and Clyde | Glasgow, United Kingdom | Not Yet Recruiting |
| Leeds Teaching Hospitals NHS Trust | Leeds, United Kingdom | Recruiting |
| London North West University Healthcare NHS Trust | London, United Kingdom | Not Yet Recruiting |
| Manchester University NHS Foundation Trus | Manchester, United Kingdom | Not Yet Recruiting |
| The Christie NHS Foundation Trust | Manchester, United Kingdom | Not Yet Recruiting |
| The Newcastle upon Tyne Hospitals NHS Foundation Trust | Newcastle, United Kingdom | Recruiting |
+ 6 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice. By subscribing you agree to our Terms of Use and Privacy Policy.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT05219058