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Study identifier: NCT05179486 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: Recruiting

Molecular Epidemiology of Biliary Tree Cancers

Condition: Cholangiocarcinoma · Malignant Digestive System Neoplasm  ·  Sponsor: M.D. Anderson Cancer Center

PhaseN/A
Planned participants1500
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
WhereHouston, Texas, United States

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study is to learn if certain risk factors (environmental, viral, behavioral, medical, and dietary), tumor markers, and genetic changes can predict the development and outcome of biliary tree cancers. Establishing biomarkers models from patients may help doctors to further understand how biliary tree cancer is affected by different treatments, and why some people's cancer responds differently than others.

This description comes directly from the study's public registry record.

Talk to the study team

Manal M Hassan  ·  713-794-5452  ·  mhassan@mdanderson.org

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Pathologically or radiologically confirmed diagnosis of CGC or GBC * With or without prior radiation or chemotherapy * All United States of America (USA) and non USA residents * No age, gender, or racial restriction * Healthy control with no current or history of cancer * Healthy controls are USA and non USA residents * Healthy controls are matched to the cases in age (5 years), gender, and race * Healthy controls are friends and spouses of patients with other than gastro-intestinal (GI) cancers * Chronic Liver Disease (CLD) controls with no current or history of cancer * CLD controls are USA and non USA residents * CLD controls are frequency matched to CGC cases by age (5 years), gender, and race * CLD controls are patients are diagnosed with or without liver biopsy (core or fine needle aspiration) * CLD controls must not have evidence liver cancer diagnosis by computed tomography (CT) or magnetic resonance imaging (MRI) Exclusion Criteria: * None

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

M D Anderson Cancer CenterHouston, Texas, United StatesRecruiting

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Houston

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