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Study identifier: NCT05047198 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingCARA-VT RCT

Catheter Ablation Versus Radio-Ablation for Ventricular Tachycardia: a Randomized Controlled Trial

Condition: Ventricular Tachycardia  ·  Sponsor: Ottawa Heart Institute Research Corporation

PhasePhase 3
Planned participants244
Who can joinAll sexes, 55 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
WhereOttawa, Ontario, Canada

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This study compares two arms - the current standard of care catheter ablation for Ventricular Tachycardia compared to stereotactic radiotherapy to non-invasively ablate ventricular tachycardia using a novel non-invasive ECG based body surface mapping technology. This allows investigators to identify ventricular tachycardia circuits to target for subsequent radio ablation. To summarize, the current standard of care invasive catheter ablation to the non-invasive radio ablation.

This description comes directly from the study's public registry record.

Talk to the study team

Calum Redpath  ·  6136967000  ·  credpath@ottawaheart.ca

Tammy Knight  ·  6136967000  ·  tknight@ottawaheart.ca

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: 1. Patient aged ≥55 years of age 2. Cardiomyopathy (Left ventricular ejection fraction ≤ 35% and ICD in situ) AND 3. Recurrent VT events despite previous CA OR 4. VT events requiring intervention and PAINESD score ≥ 15 Exclusion Criteria: 1. Patients with NYHA Class IV heart failure \&/ or with LVAD in situ 2. Patients not expected to live for more than one year for any reason 3. Patients who have previously received thoracic radiotherapy 4. Patients who are enrolled in another randomized clinical trial 5. Patients who are unable or unwilling to provide informed consent 6. Patients aged ≤54 years of age 7. Pregnancy (all women of child bearing age and potential will have a negative β-HCG test before enrollment) 8. Breastfeeding 9. Women of childbearing age who refuse to use a highly effective and medically acceptable form of contraception (IUD, sterilization, birth control implant or birth control pill) throughout the study.

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

University of Ottawa Heart InstituteOttawa, Ontario, CanadaRecruiting

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Ottawa

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