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Study identifier: NCT04896697 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Completed

Vilastobart (XTX101) Monotherapy and Vilastobart and Atezolizumab Combination Therapy in Advanced Solid Tumors

Condition: Advanced Solid Tumor  ·  Sponsor: Xilio Development, Inc.

PhasePhase 1/Phase 2
Planned participants125
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a first-in-human, Phase 1/2, multicenter, open-label study designed to evaluate the safety and tolerability of vilastobart (XTX101) as monotherapy and vilastobart (XTX101) and atezolizumab combination therapy in patients with advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (19)

Mayo Clinic HospitalPhoenix, Arizona, United States
City of HopeDuarte, California, United States
California Cancer Associates for Research and Excellence, cCAREEncinitas, California, United States
City of Hope-LennarIrvine, California, United States
USC/Norris Comprehensive Cancer CenterLos Angeles, California, United States
California Cancer Associates for Research and Excellence, cCARESan Marcos, California, United States
UCLA Hematology/Oncology- Santa MonicaSanta Monica, California, United States
City of Hope-UplandUpland, California, United States
Mayo Clinic HospitalJacksonville, Florida, United States
Sarah Cannon Research Institute at Florida Cancer SpecialistsOrlando, Florida, United States
Massachusetts General HospitalBoston, Massachusetts, United States
Mayo Clinic HospitalRochester, Minnesota, United States

+ 7 more locations — full list on the registry record.

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