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Study identifier: NCT04864054 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

Condition: Hepatocellular Carcinoma · Liver Cancer, Adult · Liver Neoplasm  ·  Sponsor: Eureka Therapeutics Inc.

PhasePhase 1/Phase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, multi-center, Phase 1/2 clinical trial evaluating the safety, tolerability, and efficacy of ECT204, an investigational ARTEMIS® T-cell therapy, in adult subjects with GPC3-positive hepatocellular carcinoma (HCC) who have experienced disease progression on, or intolerance to, prior systemic therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Teresa Klask, MBA  ·  925-949-9314  ·  Teresa.Klask@eurekainc.com

Pei Wang, PhD  ·  510-654-7045  ·  Pei.Wang@eurekainc.com

Always discuss trial participation with your own doctor first.

Locations (8)

City of HopeDuarte, California, United StatesRecruiting
Kansas University Medical Center, Principal Investigator:Westwood, Kansas, United StatesCompleted
Roswell Park Comprehensive Cancer CenterBuffalo, New York, United StatesCompleted
Montefiore Einstein Comprehensive Cancer CenterThe Bronx, New York, United StatesRecruiting
Oregon Health and Sciences UniversityPortland, Oregon, United StatesRecruiting
University of Texas Southwestern, Harold C. Simmons Comprehensive Cancer CenterDallas, Texas, United StatesRecruiting
Fred Hutchinson Cancer Center, University of WashingtonSeattle, Washington, United StatesRecruiting
National Taiwan University Cancer CenterTaipei, TaiwanRecruiting

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