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Study identifier: NCT04833335 Synced from ClinicalTrials.gov · August 08, 2026
● Study status: RecruitingGK-ASL

ASL in Brain Metastasis MRI Following Gamma Knife Treatment

Condition: Brain Metastases  ·  Sponsor: Assistance Publique - Hôpitaux de Paris

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
WhereParis, France

Interested? Contact the study team ↓

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

Arterial spin labeling (ASL) is a non-invasive MRI technique that could help the radiologists to distinguish brain metastasis progression versus radionecrosis following gamma-knife treatment. The primary target of the study is to establish the diagnostic performances (specificity, sensitivity) of quantitative measures of ASL in brain metastases suspected of progression/radionecrosis after GK treatment

This description comes directly from the study's public registry record.

Talk to the study team

Natalia SHOR, MD  ·  +330661884335  ·  shor.natalia@icloud.com

There is no obligation to join — the study team can answer your questions about taking part.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Brain metastasis from histologically proven tumor * GK treatment within 4 month prior to the inclusion * Lesions suspected of progression/ radionecrosis : i.e.≥ 25% of the size progression * Lesion size: gadolinium enhanced part of the tumour ≥1 cm Exclusion Criteria: * Pregnancy * Medical history of primitive brain tumour * MRI incompatibility/ medical history of contrast agent allergy * Claustrophobia * Patient unable to consent * Epilepsia/recent stroke * Patients participating in other studies * Patients without health care insurance

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (1)

Service de neuroradiologie, hôpital Pitié SalpêtrièreParis, FranceRecruiting

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Paris

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