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Study identifier: NCT04750902 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Completed

A Clinical Trial to Assess the Safety and the Anti-caries Efficacy of COL 101 (Arginine) Non-fluoride Dentifrices in Comparison With 0.24% Sodium Fluoride (1100 Ppm F) Dentifrice Control in 10 to 14-year-old Children

Condition: Dental Caries  ·  Sponsor: Colgate Palmolive

PhasePhase 2
Planned participants2025
Who can joinAll sexes, 10 Years to 14 Years
Healthy volunteersYes

About this study

The objective of this study is to assess the safety and to evaluate the anti-caries efficacy of COL101 (arginine) non-fluoride dentifrices compared to a 0.24% sodium fluoride dentifrice in 10-14 year-old children over a one year period.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

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Locations (9)

Loma Linda University School of DentistryLoma Linda, California, United States
University of Florida College of DentistryGainesville, Florida, United States
Indiana University School of DentistryIndianapolis, Indiana, United States
Tufts University School of Dental MedicineBoston, Massachusetts, United States
The Forsyth InstituteBoston, Massachusetts, United States
University at Buffalo School of Dental MedicineBuffalo, New York, United States
University of Pennsylvania School of Dental MedicinePhiladelphia, Pennsylvania, United States
UT Health San Antonio School of DentistrySan Antonio, Texas, United States
University of Puerto Rico School of Dental MedicineSan Juan, Puerto Rico

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