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Study identifier: NCT04720976 Synced from ClinicalTrials.gov · August 09, 2026
● Study status: Completed

JAB-3312 Based Combination Therapy in Adult Patients With Advanced Solid Tumors

Condition: Solid Tumor · NSCLC  ·  Sponsor: Allist Pharmaceuticals, Inc.

PhasePhase 1/Phase 2
Planned participants58
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNoCheck eligibility criteria ↓
Where15 locations
For sponsors, CROs & site teams
Professional view of this study — listed sites, countries and recruiting context from the public registry. Everything below is written for patients and caregivers.Open the site landscape →

About this study

To evaluate the safety and tolerability of JAB-3312 administered in investigational regimens in adult participants with advanced solid tumors.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Must have histologically or cytologically confirmed metastatic or locally advanced solid tumor. Some cohorts must meet specific expression or gene mutation where indicated * Sufficient organ function * Participants must have at least 1 measurable lesion as defined by RECIST v1.1 * Must be able to provide an archived tumor sample * ECOG performance status score of 0 or 1. Exclusion Criteria: * History of cancer that is histologically distinct from the cancers under study * Active or untreated central nervous system (CNS) metastases * History of pneumonitis or interstitial lung disease (ILD) * Has active hepatitis B, hepatitis C infection, HIV * Any severe and/or uncontrolled medical conditions * LVEF ≤50% * QTcF \>470 msec

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (15)

Research SitePhoenix, Arizona, United States
Research SiteScottsdale, Arizona, United States
Research SiteLos Angeles, California, United States
Research SiteNew Haven, Connecticut, United States
Research SiteJacksonville, Florida, United States
Research SiteOrange City, Florida, United States
Research SiteChicago, Illinois, United States
Research SiteIndianapolis, Indiana, United States
Research SiteDetroit, Michigan, United States
Research SiteRochester, Minnesota, United States
Research SiteSt Louis, Missouri, United States
Research SiteNew York, New York, United States

+ 3 more locations — full list on the registry record.

More studies in these areas

This study lists sites in the areas below. Each link shows other recruiting studies near that city, from the public registry record.

PhoenixScottsdaleLos AngelesNew Haven

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