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Study identifier: NCT04685616 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Brentuximab Vedotin in Early Stage Hodgkin Lymphoma

Condition: Hodgkin Lymphoma  ·  Sponsor: University College, London

PhasePhase 3
Planned participants1042
Who can joinAll sexes, 16 Years to 69 Years
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

RADAR is a multicentre, international, randomised, open-label phase III clinical trial composed of 2 trials running in parallel. Trial 1 will be led and sponsored by University College London (UCL) and conducted in Europe and Australia/New Zealand. Trial 2 will be led by the Canadian Cancer Trials Group (CCTG) and conducted in North America, with CCTG the regulatory sponsor in Canada, and University of Miami the regulatory sponsor and IND holder in the US. Datasets from Trial 1 and Trial 2 will be combined to achieve the total sample size. Data analysis will be performed by UCL and therefore UCL is responsible for the clinicaltrials.gov entry. Eligible patients will be randomised to receive either ABVD or A2VD chemotherapy. An interim PET-CT scan will be performed after 2 cycles of treatment, which will be used to adapt subsequent treatment. Patients will receive a total of 3-4 cycles of chemotherapy and may also receive involved site radiotherapy as consolidation. Patients will be followed up for a minimum of 5 years after treatment.

This description comes directly from the study's public registry record.

Talk to the study team

RADAR Trial Coordinator  ·  +44(0)207 679 9860  ·  ctc.radar@ucl.ac.uk

Always discuss trial participation with your own doctor first.

Locations (72)

Stanford University - (Stanford Cancer Institute)Stanford, California, United StatesRecruiting
University of Miami School of MedicineMiami, Florida, United StatesRecruiting
Memorial Sloan Kettering Cancer CenterNew York, New York, United StatesRecruiting
Royal North Shore HospitalSaint Leonards, New South Wales, AustraliaRecruiting
Townsville University HospitalTownsville, Queensland, AustraliaRecruiting
Royal Adelaide HospitalAdelaide, AustraliaRecruiting
Box Hill HospitalBox Hill, AustraliaRecruiting
Royal Brisbane and Women's HospitalBrisbane, AustraliaRecruiting
Royal Darwin HospitalDarwin, AustraliaRecruiting
Liverpool HospitalLiverpool, AustraliaRecruiting
Sunshine Hospital (Western Health)Melbourne, AustraliaRecruiting
Concord Repatriation General HospitalSydney, AustraliaRecruiting

+ 60 more locations — full list on the registry record.

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