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Study identifier: NCT04433546 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Terminated

Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS).

Condition: Acute Respiratory Distress Syndrome · Coronavirus · Hypoxic Respiratory Failure  ·  Sponsor: PhaseBio Pharmaceuticals Inc.

PhasePhase 2
Planned participants54
Who can joinAll sexes, 18 Years to 85 Years
Healthy volunteersNo

About this study

This is a multicenter, randomized, double-blind, parallel group study to investigate the efficacy of pemziviptadil (PB1046) by improving the clinical outcomes in hospitalized COVID-19 patients at high risk for rapid clinical deterioration, acute respiratory distress syndrome (ARDS) and death. The study will enroll approximately 210 hospitalized COVID-19 patients who require urgent decision-making and treatment at approximately 20 centers in the United States.

This description comes directly from the study's public registry record.

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Locations (4)

Baptist Health Research InstituteJacksonville, Florida, United States
Sarasota Memorial HospitalSarasota, Florida, United States
The University of Kansas Medical CenterKansas City, Kansas, United States
Adventist Healthcare White Oak Medical CenterSilver Spring, Maryland, United States

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