EICHORCondition: DLBCL · Diffuse Large B Cell Lymphoma · Sponsor: Nordic Lymphoma Group
Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.
This is a phase III, randomized, open-label, multicenter trial, conducted in Sweden, Norway, Finland, Denmark, Italy, Australia and New Zealand, in elderly patients with untreated diffuse large B-cell lymphoma. Elderly is defined as either ≥80 years of age, or ≥75 years and frail, according to a simplified Comprehensive Geriatric Assessment. Patients will be randomized 1:1 to either the standard treatment for this population, R-miniCHOP, or an experimental regimen, R-pola-miniCHP, where vincristine is substituted by an immunoconjugate, polatuzumab vedotin. The duration of the screening period is up to 4 weeks. The duration of active treatment is 18 weeks in both arms, and patients will be followed up to 36 months after end of treatment. Start of enrollment is planned in Q1 2020, and the last visit of the last patient included (end of trial) is estimated in Q1 2027.
This description comes directly from the study's public registry record.
Mats Jerkeman · 0046704973507 · mats.jerkeman@med.lu.se
Always discuss trial participation with your own doctor first.
| Border Medical Oncology Research Unit | Albury, Australia | Not Yet Recruiting |
| Royal Prince Alfred Hospital | Camperdown, Australia | Recruiting |
| Coffs Harbour | Coffs Harbour, Australia | Not Yet Recruiting |
| Concord Repatriation General Hospital | Concord, Australia | Recruiting |
| Tweed Valley Hospital | Cudgen, Australia | Not Yet Recruiting |
| The Canberra Hospital | Garran, Australia | Not Yet Recruiting |
| Royal Hobart Hospital | Hobart, Australia | Not Yet Recruiting |
| Liverpool | Liverpool, Australia | Recruiting |
| Bendigo | Melbourne, Australia | Not Yet Recruiting |
| Northern Health | Melbourne, Australia | Not Yet Recruiting |
| St Vincent's Hospital Melbourne | Melbourne, Australia | Recruiting |
| Western Health | Melbourne, Australia | Not Yet Recruiting |
+ 57 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT04332822