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Study identifier: NCT04228991 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Active Not Recruiting

Hypofractionated LocoRegional Radiotherapy in Breast Cancer

Condition: Breast Neoplasms · Radiotherapy · Lymphedema  ·  Sponsor: Ontario Clinical Oncology Group (OCOG)

PhasePhase 3
Planned participants588
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

The primary objective of this study is to determine if hypofractionated RT delivered over 1 week to the breast or chest wall and regional nodes (26Gy in 5 daily fractions) following BCS or mastectomy, is non-inferior to conventional fractionation to the breast or chest wall and regional nodes delivered over 3 weeks (40Gy in 15 daily fractions) in patients with node-positive breast cancer.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (20)

Tom Baker Cancer CentreCalgary, Alberta, Canada
Cross Cancer InstituteEdmonton, Alberta, Canada
BC Cancer - Centre for the Southern InteriorKelowna, British Columbia, Canada
BC Cancer - Centre for the NorthPrince George, British Columbia, Canada
BC Cancer - Vancouver CentreVancouver, British Columbia, Canada
BC Cancer - Vancouver Island CentreVictoria, British Columbia, Canada
Northeast Cancer Centre, Health Sciences NorthGreater Sudbury, Ontario, Canada
Juravinski Cancer CentreHamilton, Ontario, Canada
London Regional Cancer ProgramLondon, Ontario, Canada
The Ottawa Hospital Regional Cancer CentreOttawa, Ontario, Canada
Sunnybrook Health Sciences Centre - Odette Cancer CentreToronto, Ontario, Canada
Princess Margaret Cancer Centre - UHNToronto, Ontario, Canada

+ 8 more locations — full list on the registry record.

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