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Study identifier: NCT04197479 Synced from ClinicalTrials.gov · August 06, 2026
● Study status: Completed

A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease Patients

Condition: Non-Alcoholic Fatty Liver Disease  ·  Sponsor: Madrigal Pharmaceuticals, Inc.

PhasePhase 3
Planned participants1343
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

A double-blind placebo controlled randomized Phase 3 study to evaluate the safety and tolerability of once-daily, oral administration of 80 or 100 mg resmetirom versus matching placebo. At least 100 patients will be enrolled in a 100 mg open-label arm and will include a special safety population (eg, patients with compensated NASH cirrhosis).

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Locations (77)

Central Research AssociatesBirmingham, Alabama, United States
Arizona Liver Health - ChandlerChandler, Arizona, United States
East Valley Family PhysiciansChandler, Arizona, United States
The Institute For Liver Health - GlendaleGlendale, Arizona, United States
Arizona - Desert Clinical ResearchMesa, Arizona, United States
The Institute For Liver Health - TucsonTucson, Arizona, United States
Adobe GastroenterologyTucson, Arizona, United States
Arkansas GastroenterologyNorth Little Rock, Arkansas, United States
Fresno Clinical Research CenterFresno, California, United States
National Research Institute - Huntington ParkHuntington Park, California, United States
Ruane Clinical Research GroupLos Angeles, California, United States
National Research Institute - Los AngelesLos Angeles, California, United States

+ 65 more locations — full list on the registry record.

Sponsor or site team? See the site landscape for this trial — listed sites, countries, and recruiting-density context.

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