EICHORCondition: Obesity · HIV-1-infection · Sponsor: University College Dublin
The prevalence of obesity is rising worldwide, both in low- and high-income countries, including people with HIV (PWH). Semaglutide's efficacy in achieving weight loss in obese PWH is still unexplored. The aim of this study is to assess the efficacy and safety of semaglutide in achieving greater weight loss compared to diet and excercise alone in obese PWH and to explore the effect of semaglutide on the immune function, markers of immune activation, viral reservoir, markers of glucose and lipid metabolism and gut microbiome.
This description comes directly from the study's public registry record.
Stefano Savinelli, MD · +3532215014 · stefano.savinelli1@ucd.ie
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| Mater Misericordiae University Hospital | Dublin, Dublin, Ireland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT04174755