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Study identifier: NCT04159142 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Recruiting

Nab-paclitaxel Plus Carboplatin Versus Nab-paclitaxel Plus Capecitabine in the Treatment of Advanced Triple-negative Breast Cancer

Condition: Triple Negative Breast Cancer · Nab-paclitaxel  ·  Sponsor: Hebei Medical University Fourth Hospital

PhasePhase 2
Planned participants414
Who can joinFemale, 18 Years to 70 Years
Healthy volunteersNo

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About this study

This is a multi-center , open-lable clinical trial. Triple-negative breast cancer (TNBC) is a term applied to breast cancer cases that have \<1% expression of the estrogen receptor (ER) and the progesterone receptor (PR) and do not over express HER2. TNBC is diagnosed in 15-20% of breast cancer cases and tends to occur in younger women and have biologically more aggressive high grade disease. The purpose of this study is to assess the efficacy and safety of the following two combinations: i) nab-paclitaxel+carboplatin; ii) nab-paclitaxel+capecitabine in subjects with advanced TNBC and up to one prior line of systemic treatment for metastatic disease. Maintenance therapy with capecitabine after completion of combination chemotherapy.

This description comes directly from the study's public registry record.

Talk to the study team

Cuizhi Geng, M.D.  ·  0311-6669 6310  ·  gengcuizhi@hotmail.com

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Locations (1)

The Fourth Hospital of Hebei Medical UniversityShijiazhuang, Hebei, ChinaRecruiting

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