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Study identifier: NCT04140695 Synced from ClinicalTrials.gov · August 07, 2026
● Study status: Terminated

Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE2)

Condition: Atopic Dermatitis  ·  Sponsor: Vanda Pharmaceuticals

PhasePhase 3
Planned participants87
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNoCheck eligibility criteria ↓
Where51 locations

Sponsor, CRO or site team? See where this study is running → — listed sites, countries and recruiting context. Everything below is written for patients and caregivers.

About this study

This is a multicenter, randomized, double-blind, placebo-controlled study to be conducted in the United States in subjects with atopic dermatitis.

This description comes directly from the study's public registry record.

Talk to the study team

No contact information is available for this study as per the public registry record.

Always discuss trial participation with your own doctor first.

Full eligibility criteria (exactly as the study team wrote them)

Inclusion Criteria: * Male and non-pregnant, non-lactating female patients aged 18 - 70 years (inclusive); * Diagnosed with atopic dermatitis; * Suffering from chronic pruritus; * Body Mass Index (BMI) of ≥18 and ≤40 kg/m2 Exclusion Criteria: * Chronic pruritus due to condition other than atopic dermatitis (AD); * A positive test for drugs of abuse at the screening or evaluation visits; * Exposure to any investigational medication in the past 60 days

Reproduced word-for-word from the public registry record — the study team can answer questions about it.

Locations (51)

Vanda Investigational SiteHoover, Alabama, United States
Vanda Investigational SiteTempe, Arizona, United States
Vanda Investigational SiteEncino, California, United States
Vanda Investigational SiteFountain Valley, California, United States
Vanda Investigational SiteLaguna Hills, California, United States
Vanda Investigational SiteLomita, California, United States
Vanda Investigational SiteLos Angeles, California, United States
Vanda Investigational SiteLos Angeles, California, United States
Vanda Investigational SiteLos Angeles, California, United States
Vanda Investigational SiteDenver, Colorado, United States
Vanda Investigational SiteClearwater, Florida, United States
Vanda Investigational SiteMiami, Florida, United States

+ 39 more locations — full list on the registry record.

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